WebMay 19, 2024 · Similarly, lineage formation has been observed for the MCF-7 breast cancer and human embryonic kidney 293 (HEK293) cell lines, leading to substantial phenotypic … WebMar 5, 2024 · In that reduced dimensional space, a cell’s pseudotime for a given lineage is the distance, along the lineage, between the cell and the origin of the lineage. ... Bulk RNA-seq time-course data ...
Digital development: a database of cell lineage differentiation in C ...
WebApr 19, 2024 · Central to the core principle of cell theory, depicting cells’ history, state and fate is a fundamental goal in modern biology. By leveraging clonal analysis and single-cell RNA-seq technologies, single-cell lineage tracing provides new opportunities to interrogate both cell states and lineage histories. During the past few years, many strategies to … WebSep 5, 2024 · Cells in the UMAP space were clustered using the Louvain algorithm . For each cell, the age of the embryo from which it came (i.e., the embryo time) was estimated by correlating its transcriptome with a bulk RNA-seq time series . Cells were then manually annotated with their corresponding cell type and lineage, as described in the main text. cr カップ 時間
Cell Lineage - an overview ScienceDirect Topics
WebThe well-documented cell lineage of C. elegans tells us the exact lineal relationship between any pair of cells, uniquely allowing us to compare transcriptomes in both space and time. To analyze whether cell-specific features of the transcriptome were maintained over time, we generated a correlation matrix comparing the transcriptomes of all ... WebApr 3, 2024 · The cells of some organisms, such as C. elegans, have invariant lineages between individuals, whereas vertebrate cell lineage patterns are more variable. Latest … WebSep 8, 2024 · The single cells were passed through a 40–100 μm sieve and spun down at 400g at 4 °C for 10 min. Red cell lysis solution (eBioscience10X RBC Lysis Buffer (Multi-species)) was used according to ... cr カップ 最後 なぜ